Orforglipron hemicalcium hydrate
;)
Orforglipron
;)
5-((S)-2,2-dimethyltetrahydro-2H-pyran-4-yl)-1-((1S,2S)-2-methyl-1-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)cyclopropyl)-1H-indole-2-carboxylic acid
Orforglipron Intermediate
;)
(S)-5-(2,2-Dimethyltetrahydro-2H-pyran-4-yl)-1H-indole-2-carboxylic acid
Orforglipron Intermediate
;)
1-[(1S,2S)-1-cyano-2-methylcyclopropyl]-5-[(4S)-2,2-dimethyloxan-4-yl]-N-methyl-N-phenylindole-2-carboxamide
Orforglipron Intermediate
;)
Ethyl (S)-5-(2,2-dimethyltetrahydro-2H-pyran-4-yl)-1H-indole-2-carboxylate
Orforglipron Intermediate
;)
(S)-1-(Cyanomethyl)-5-(2,2-dimethyltetrahydro-2H-pyran-4-yl)-N-methyl-N-phenyl-1H-indole-2-carboxamide
Orforglipron Intermediate
;)
(S)-5-(2,2-dimethyltetrahydro-2H-pyran-4-yl)-N-methyl-N-phenyl-1H-indole-2-carboxamide
Orforglipron Intermediate
;)
(S)-1-(4-Fluoro-1-methyl-1H-indazol-5-yl)-3-(2-(4-fluoro-3,5-dimethylphenyl)-4-methyl-4,5,6,7-tetrahydro-2H-pyrazolo[4,3-c]pyridin-3-yl)-1H-imidazol-2(3H)-one
Orforglipron Intermediate
;)
tert-butyl (S)-2-(4-fluoro-3,5-dimethylphenyl)-4-methyl-3-(2-oxo-2,3-dihydro-1H-imidazol-1-yl)-2,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridine-5-carboxylate
Orforglipron Intermediate
;)
Methyl 4-aminopyridine-2-carboxylate
;)
3,4-Difluoro-2-methoxyphenylacetic acid
;)
(R)-4,4,4-Trifluoro-3-hydroxy-3-methylbutan-2-one
;)
Fmoc-4-[2-(Boc-amino)ethoxy]-L-Phenylalanine
;)
Tert-butyl (R)-(1-(1H-indol-3-yl)propan-2-yl)carbamate
;)
tert-butyl (R)-4-methyl-1,2,3-oxathiazolidine-3-carboxylate 2,2-dioxide
;)
Ethyl [(4-mercapto-2-methylphenyl)oxy]acetate
;)
4-(Trifluoromethyl) Phenol
;)
5-Bromoindole-2-carboxylic Acid
Orforglipron starting material
;)
(4S)-3-Amino-2-(4-fluoro-3,5-dimethylphenyl)-4-methyl-6,7-dihydro-4H-pyrazolo[4,3-c]pyridine-5-carboxylic acid tert-butyl ester
Orforglipron starting material
;)
N-Boc-L-alaninol
Orforglipron starting material
;)
